Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines

The CreER(T2)/loxP system is widely used to induce conditional gene deletion in mice. One of the main advantages of the system is that Cre-mediated recombination can be controlled in time through Tamoxifen administration. This has allowed researchers to study the function of embryonic lethal genes a...

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Detalles Bibliográficos
Autores principales: Álvarez-Aznar, A., Martínez-Corral, I., Daubel, N., Betsholtz, C., Mäkinen, T., Gaengel, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000517/
https://www.ncbi.nlm.nih.gov/pubmed/31641921
http://dx.doi.org/10.1007/s11248-019-00177-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000517/
https://www.ncbi.nlm.nih.gov/pubmed/31641921
http://dx.doi.org/10.1007/s11248-019-00177-8

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