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M3C: Monte Carlo reference-based consensus clustering

Genome-wide data is used to stratify patients into classes for precision medicine using clustering algorithms. A common problem in this area is selection of the number of clusters (K). The Monti consensus clustering algorithm is a widely used method which uses stability selection to estimate K. Howe...

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Detalles Bibliográficos
Autores principales: John, Christopher R., Watson, David, Russ, Dominic, Goldmann, Katriona, Ehrenstein, Michael, Pitzalis, Costantino, Lewis, Myles, Barnes, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000518/
https://www.ncbi.nlm.nih.gov/pubmed/32020004
http://dx.doi.org/10.1038/s41598-020-58766-1