On the prevention of kidney uptake of radiolabeled DARPins

BACKGROUND: Designed ankyrin repeat proteins (DARPins) are small engineered scaffold proteins (14–18 kDa) that demonstrated promising tumor-targeting properties in preclinical studies. However, high renal accumulation of activity for DARPins labeled with residualizing labels is a limitation for targ...

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Detalles Bibliográficos
Autores principales: Altai, Mohamed, Garousi, Javad, Rinne, Sara S., Schulga, Alexey, Deyev, Sergey, Vorobyeva, Anzhelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000568/
https://www.ncbi.nlm.nih.gov/pubmed/32020413
http://dx.doi.org/10.1186/s13550-020-0599-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000568/
https://www.ncbi.nlm.nih.gov/pubmed/32020413
http://dx.doi.org/10.1186/s13550-020-0599-1

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