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Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis
BACKGROUND: Animal studies reporting immune checkpoint inhibitors (CPIs) improved host defense and survival during bacterial sepsis provided one basis for phase I CPI sepsis trials. We performed a systematic review and meta-analysis examining the benefit of CPI therapy in preclinical studies, and wh...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000606/ https://www.ncbi.nlm.nih.gov/pubmed/32020483 http://dx.doi.org/10.1186/s40635-019-0290-x |