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MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a main complication of diabetes mellitus (DM). Recent studies have implicated microRNAs in human retinal microvascular endothelial cell (HRMEC) dysfunction. In this study, we aim to investigate the apoptotic promotion of miR-29b-3p by blocking SIRT1 in HRMEC...

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Detalles Bibliográficos
Autores principales: Zeng, Yong, Cui, Zekai, Liu, Jian, Chen, Jiansu, Tang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000655/
https://www.ncbi.nlm.nih.gov/pubmed/32063865
http://dx.doi.org/10.3389/fphys.2019.01621