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BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner

The efficient and reproducible derivation and maturation of multipotent hematopoietic progenitors from human pluripotent stem cells (hPSCs) requires the recapitulation of appropriate developmental stages and the microenvironment. Here, using serum-, xeno-, and feeder-free stepwise hematopoietic indu...

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Detalles Bibliográficos
Autores principales: Jeong, Suji, An, Borim, Kim, Jung-Hyun, Han, Hyo-Won, Heo, Hye-Ryeon, Ha, Kwon-Soo, Han, Eun-Taek, Park, Won Sun, Hong, Seok-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000736/
https://www.ncbi.nlm.nih.gov/pubmed/31956269
http://dx.doi.org/10.1038/s12276-019-0357-5