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Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX

Cancer cells go through a process known as epithelial–mesenchymal transition (EMT) during which they acquire the ability to migrate and invade extracellular matrix. Some cells also acquire the ability to move across a layer of endothelial cells to enter and exit the bloodstream; intra- and extravasa...

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Detalles Bibliográficos
Autores principales: Marcolino, Eudmar, Siddiqui, Yusra Hasan, van den Bosch, Marion, Poole, Alastair W., Jayaraman, Padma-Sheela, Gaston, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000753/
https://www.ncbi.nlm.nih.gov/pubmed/32019914
http://dx.doi.org/10.1038/s41389-020-0189-0