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DNA repair by Rad52 liquid droplets

Cellular processes are influenced by liquid phase separation, but its role in DNA repair is unclear. Here, we show that in Saccharomyces cerevisiae, liquid droplets made up of DNA repair proteins cooperate with different types of DNA damage-inducible intranuclear microtubule filaments (DIMs) to prom...

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Detalles Bibliográficos
Autores principales: Oshidari, Roxanne, Huang, Richard, Medghalchi, Maryam, Tse, Elizabeth Y. W., Ashgriz, Nasser, Lee, Hyun O., Wyatt, Haley, Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000754/
https://www.ncbi.nlm.nih.gov/pubmed/32019927
http://dx.doi.org/10.1038/s41467-020-14546-z