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ROR1 regulates chemoresistance in Breast Cancer via modulation of drug efflux pump ABCB1

Chemoresistance is one of the leading causes of mortality in breast cancer (BC). Understanding the molecules regulating chemoresistance is critical in order to combat chemoresistant BC. Drug efflux pump ABCB1 is overexpressed in chemoresistant neoplasms where it effluxes various chemotherapeutic age...

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Detalles Bibliográficos
Autores principales: Fultang, Norman, Illendula, Abhinav, Lin, Jianhuang, Pandey, Manoj K., Klase, Zachary, Peethambaran, Bela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000766/
https://www.ncbi.nlm.nih.gov/pubmed/32020017
http://dx.doi.org/10.1038/s41598-020-58864-0