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A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response

Long non-coding (lnc) RNAs represent a fascinating class of transcripts that remains highly controversial mainly due to ambiguity surrounding overall biological relevance of these RNAs. Multitude of reverse genetics studies showing functionality of lncRNAs are unfortunately based on assays that are...

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Detalles Bibliográficos
Autores principales: Xu, Dongyang, Cai, Ye, Tang, Lu, Han, Xueer, Gao, Fan, Cao, Huifen, Qi, Fei, Kapranov, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000768/
https://www.ncbi.nlm.nih.gov/pubmed/32020014
http://dx.doi.org/10.1038/s41598-020-58104-5