DNA unwinding mechanism of a eukaryotic replicative CMG helicase

High-resolution structures have not been reported for replicative helicases at a replication fork at atomic resolution, a prerequisite to understanding the unwinding mechanism. The eukaryotic replicative CMG (Cdc45, Mcm2-7, GINS) helicase contains a Mcm2-7 motor ring, with the N-tier ring in front a...

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Detalles Bibliográficos
Autores principales: Yuan, Zuanning, Georgescu, Roxana, Bai, Lin, Zhang, Dan, Li, Huilin, O’Donnell, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000775/
https://www.ncbi.nlm.nih.gov/pubmed/32019936
http://dx.doi.org/10.1038/s41467-020-14577-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000775/
https://www.ncbi.nlm.nih.gov/pubmed/32019936
http://dx.doi.org/10.1038/s41467-020-14577-6

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