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Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity

Increased extracellular volume (ECV) by CMR is a marker of interstitial myocardial fibrosis and is associated with diastolic dysfunction in sickle cell anemia (SCA). Left atrial (LA) dysfunction and stiffness contribute to the development of diastolic heart failure in other settings. We aimed to eva...

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Detalles Bibliográficos
Autores principales: Alsaied, Tarek, Niss, Omar, Tretter, Justin T., Powell, Adam W., Chin, Clifford, Fleck, Robert J., Cnota, James F., Malik, Punam, Quinn, Charles T., Nagueh, Sherif M., Taylor, Michael D., Mazur, Wojciech M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000788/
https://www.ncbi.nlm.nih.gov/pubmed/32019991
http://dx.doi.org/10.1038/s41598-020-58662-8