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Development and characterization of pellets for targeted delivery of 5-fluorouracil and phytic acid for treatment of colon cancer in Wistar rat

The present study was designed to investigate the therapeutic efficacy of metal chelator and anticancer drug in the treatment of colorectal cancer (CRC). Pellets containing Phytic acid, 5- Fluorouracil (5-FU), Microcrystalline cellulose (MCC) PH 101, Hydroxypropyl Methylcellulose (HPMC) and Barium s...

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Detalles Bibliográficos
Autores principales: Kaur, Veerpal, Goyal, Amit K., Ghosh, Goutam, Chandra Si, Sudam, Rath, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000805/
https://www.ncbi.nlm.nih.gov/pubmed/32042938
http://dx.doi.org/10.1016/j.heliyon.2019.e03125