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TNF-α increases breast cancer stem-like cells through up-regulating TAZ expression via the non-canonical NF-κB pathway

Breast cancer patients often suffer from disease relapse and metastasis due to the presence of breast cancer stem-like cells (BCSCs). Numerous studies have reported that high levels of inflammatory factors, including tumor necrosis factor alpha (TNF-α), promote BCSCs. However, the mechanism by which...

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Detalles Bibliográficos
Autores principales: Liu, Wenjing, Lu, Xiaoqing, Shi, Peiguo, Yang, Guangxi, Zhou, Zhongmei, Li, Wei, Mao, Xiaoyun, Jiang, Dewei, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000832/
https://www.ncbi.nlm.nih.gov/pubmed/32019974
http://dx.doi.org/10.1038/s41598-020-58642-y