Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program

Differentiating neutrophils undergo large-scale changes in nuclear morphology. How such alterations in structure are established and modulated upon exposure to microbial agents is largely unknown. Here, we found that prior to encounter with bacteria, an armamentarium of inflammatory genes was positi...

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Detalles Bibliográficos
Autores principales: Denholtz, Matthew, Zhu, Yina, He, Zhaoren, Lu, Hanbin, Isoda, Takeshi, Döhrmann, Simon, Nizet, Victor, Murre, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000913/
https://www.ncbi.nlm.nih.gov/pubmed/31919189
http://dx.doi.org/10.1101/gad.333708.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000913/
https://www.ncbi.nlm.nih.gov/pubmed/31919189
http://dx.doi.org/10.1101/gad.333708.119

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