SINEUP Non-coding RNA Targeting GDNF Rescues Motor Deficits and Neurodegeneration in a Mouse Model of Parkinson’s Disease

Glial cell-derived neurotrophic factor (GDNF) has a potent action in promoting the survival of dopamine (DA) neurons. Several studies indicate that increasing GDNF levels may be beneficial for the treatment of Parkinson’s disease (PD) by reducing neurodegeneration of DA neurons. Despite a plethora o...

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Detalles Bibliográficos
Autores principales: Espinoza, Stefano, Scarpato, Margherita, Damiani, Devid, Managò, Francesca, Mereu, Maddalena, Contestabile, Andrea, Peruzzo, Omar, Carninci, Piero, Santoro, Claudio, Papaleo, Francesco, Mingozzi, Federico, Ronzitti, Giuseppe, Zucchelli, Silvia, Gustincich, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000958/
https://www.ncbi.nlm.nih.gov/pubmed/31495777
http://dx.doi.org/10.1016/j.ymthe.2019.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000958/
https://www.ncbi.nlm.nih.gov/pubmed/31495777
http://dx.doi.org/10.1016/j.ymthe.2019.08.005

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