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Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor/transcription factor that modulates several cellular and immunological processes following activation by pathogen-associated stimuli, though its role during virus infection is largely unknown. Here, we show that AhR is activated in cells...

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Detalles Bibliográficos
Autores principales: Grunewald, Matthew E., Shaban, Mohamed G., Mackin, Samantha R., Fehr, Anthony R., Perlman, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000979/
https://www.ncbi.nlm.nih.gov/pubmed/31694960
http://dx.doi.org/10.1128/JVI.01743-19