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METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing

Epigenetic alterations contributed to human carcinogenesis immensely. N6-methyladenosine (m6A) is one of the most preventive and abundant modifications on RNA molecules present in eukaryotes. However, the biological function of m6A methylation in colorectal cancer (CRC) remains largely unclear. Here...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Sun, Li, Pan, Bei, He, Bangshun, Pan, Yuqin, Sun, Huiling, Xia, Xinyi, Wang, Shukui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001002/
https://www.ncbi.nlm.nih.gov/pubmed/31839484
http://dx.doi.org/10.1016/j.ymthe.2019.11.016