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Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D

Sarcomas are malignancies of mesenchymal origin that occur in bone and soft tissues. Many are chemo- and radiotherapy resistant, thus conventional treatments fail to increase overall survival. Natural Killer (NK) cells exert anti-tumor activity upon detection of a complex array of tumor ligands, but...

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Detalles Bibliográficos
Autores principales: Sayitoglu, Ece Canan, Georgoudaki, Anna-Maria, Chrobok, Michael, Ozkazanc, Didem, Josey, Benjamin J., Arif, Muhammad, Kusser, Kim, Hartman, Michelle, Chinn, Tamara M., Potens, Renee, Pamukcu, Cevriye, Krueger, Robin, Zhang, Cheng, Mardinoglu, Adil, Alici, Evren, Temple, Harry Thomas, Sutlu, Tolga, Duru, Adil Doganay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001093/
https://www.ncbi.nlm.nih.gov/pubmed/32082316
http://dx.doi.org/10.3389/fimmu.2020.00040