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Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D
Sarcomas are malignancies of mesenchymal origin that occur in bone and soft tissues. Many are chemo- and radiotherapy resistant, thus conventional treatments fail to increase overall survival. Natural Killer (NK) cells exert anti-tumor activity upon detection of a complex array of tumor ligands, but...
Autores principales: | Sayitoglu, Ece Canan, Georgoudaki, Anna-Maria, Chrobok, Michael, Ozkazanc, Didem, Josey, Benjamin J., Arif, Muhammad, Kusser, Kim, Hartman, Michelle, Chinn, Tamara M., Potens, Renee, Pamukcu, Cevriye, Krueger, Robin, Zhang, Cheng, Mardinoglu, Adil, Alici, Evren, Temple, Harry Thomas, Sutlu, Tolga, Duru, Adil Doganay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001093/ https://www.ncbi.nlm.nih.gov/pubmed/32082316 http://dx.doi.org/10.3389/fimmu.2020.00040 |
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