Identification of pAKT as a pharmacodynamic marker for MER kinase in human melanoma G361 cells

BACKGROUND: The MER signaling pathway represents an attractive therapeutic target for human cancers. Growth arrest–specific protein 6 (GAS6)–induced MER phosphorylation is often unstable and difficult to detect without pervanadate pretreatment in human cancer cells, posing a challenge for the develo...

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Detalles Bibliográficos
Autores principales: Chen, Yaoyu, Favata, Margaret, Pusey, Michelle, Li, Jun, Lo, Yvonne, Ye, Min, Wynn, Richard, Wang, Xiaozhao, Yao, Wenqing, Chen, Yingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001211/
https://www.ncbi.nlm.nih.gov/pubmed/32042425
http://dx.doi.org/10.1186/s40364-020-0184-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001211/
https://www.ncbi.nlm.nih.gov/pubmed/32042425
http://dx.doi.org/10.1186/s40364-020-0184-9

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