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Identification of pAKT as a pharmacodynamic marker for MER kinase in human melanoma G361 cells

BACKGROUND: The MER signaling pathway represents an attractive therapeutic target for human cancers. Growth arrest–specific protein 6 (GAS6)–induced MER phosphorylation is often unstable and difficult to detect without pervanadate pretreatment in human cancer cells, posing a challenge for the develo...

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Detalles Bibliográficos
Autores principales:	Chen, Yaoyu, Favata, Margaret, Pusey, Michelle, Li, Jun, Lo, Yvonne, Ye, Min, Wynn, Richard, Wang, Xiaozhao, Yao, Wenqing, Chen, Yingnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001211/ https://www.ncbi.nlm.nih.gov/pubmed/32042425 http://dx.doi.org/10.1186/s40364-020-0184-9

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