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R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability

OBJECTIVE: R-spondin 2 (RSPO2) is required for lung morphogenesis, activates Wnt signaling, and is upregulated in idiopathic lung fibrosis. Our objective was to investigate whether RSPO2 is similarly important in homeostasis of the adult lung. While investigating the characteristics of bronchoalveol...

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Detalles Bibliográficos
Autores principales: Jackson, S. R., Costa, M. F. D. M., Pastore, C. F., Zhao, G., Weiner, A. I., Adams, S., Palashikar, G., Quansah, K., Hankenson, K., Herbert, D. R., Vaughan, A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001225/
https://www.ncbi.nlm.nih.gov/pubmed/32019591
http://dx.doi.org/10.1186/s13104-020-4930-8