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Targeted next-generation sequencing identifies novel variants in candidate genes for Parkinson’s disease in Black South African and Nigerian patients

BACKGROUND: The prevalence of Parkinson’s disease (PD) is increasing in sub-Saharan Africa, but little is known about the genetics of PD in these populations. Due to their unique ancestry and diversity, sub-Saharan African populations have the potential to reveal novel insights into the pathobiology...

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Detalles Bibliográficos
Autores principales: Oluwole, Oluwafemi G., Kuivaniemi, Helena, Abrahams, Shameemah, Haylett, William L., Vorster, Alvera A., van Heerden, Carel J., Kenyon, Colin P., Tabb, David L., Fawale, Michael B., Sunmonu, Taofiki A., Ajose, Abiodun, Olaogun, Matthew O., Rossouw, Anastasia C., van Hillegondsberg, Ludo S., Carr, Jonathan, Ross, Owen A., Komolafe, Morenikeji A., Tromp, Gerard, Bardien, Soraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001245/
https://www.ncbi.nlm.nih.gov/pubmed/32019516
http://dx.doi.org/10.1186/s12881-020-0953-1