Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis

BACKGROUND: Multiple sclerosis (MS) is a chronic debilitating immune-mediated disease of the central nervous system (CNS) driven by demyelination and gray matter neurodegeneration. We previously reported an experimental autoimmune encephalomyelitis (EAE) MS mouse model with elevated serum CXCL1 that...

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Detalles Bibliográficos
Autores principales: Khaw, Yee Ming, Cunningham, Claire, Tierney, Abigail, Sivaguru, Mayandi, Inoue, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001284/
https://www.ncbi.nlm.nih.gov/pubmed/32019585
http://dx.doi.org/10.1186/s12974-020-1730-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001284/
https://www.ncbi.nlm.nih.gov/pubmed/32019585
http://dx.doi.org/10.1186/s12974-020-1730-y

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