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CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation
BACKGROUND: Ischemic stroke is a main cause of mortality. Blood-brain barrier (BBB) breakdown appears to play a critical role in inflammation in patients with ischemic stroke and acceleration of brain injury. The BBB has a protective function and is composed of endothelial cells, pericytes, and astr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001304/ https://www.ncbi.nlm.nih.gov/pubmed/32019570 http://dx.doi.org/10.1186/s12974-020-1727-6 |