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Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation

Protein glycosylation plays essential roles in protein structure, stability, and activity such as cell adhesion. The cadherin superfamily of adhesion molecules carry O-linked mannose glycans at conserved sites and it was recently demonstrated that the transmembrane and tetratricopeptide repeat-conta...

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Detalles Bibliográficos
Autores principales: Graham, Jill B., Sunryd, Johan C., Mathavan, Ketan, Weir, Emma, Larsen, Ida Signe Bohse, Halim, Adnan, Clausen, Henrik, Cousin, Hélène, Alfandari, Dominque, Hebert, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001481/
https://www.ncbi.nlm.nih.gov/pubmed/31851597
http://dx.doi.org/10.1091/mbc.E19-07-0408