Mechanistic insights into the inhibition of NTCP by myrcludex B

BACKGROUND & AIMS: The sodium taurocholate co-transporting polypeptide (NTCP) is the entry receptor for the hepatitis B and delta virus (HBV/HDV) and the main hepatic uptake transporter of conjugated bile acids. Myrcludex B, a synthetic peptide mimicking the NTCP-binding domain of HBV, blocks HB...

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Detalles Bibliográficos
Autores principales: Donkers, Joanne M., Appelman, Monique D., van de Graaf, Stan F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001544/
https://www.ncbi.nlm.nih.gov/pubmed/32039379
http://dx.doi.org/10.1016/j.jhepr.2019.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001544/
https://www.ncbi.nlm.nih.gov/pubmed/32039379
http://dx.doi.org/10.1016/j.jhepr.2019.07.006

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