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Mechanistic insights into the inhibition of NTCP by myrcludex B
BACKGROUND & AIMS: The sodium taurocholate co-transporting polypeptide (NTCP) is the entry receptor for the hepatitis B and delta virus (HBV/HDV) and the main hepatic uptake transporter of conjugated bile acids. Myrcludex B, a synthetic peptide mimicking the NTCP-binding domain of HBV, blocks HB...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001544/ https://www.ncbi.nlm.nih.gov/pubmed/32039379 http://dx.doi.org/10.1016/j.jhepr.2019.07.006 |