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Retrospective cohort study monitoring PEG-asparaginase activity in acute lymphoblastic leukemia patients with and without premedication

Background: PEG-L-asparaginase (pegaspargase) is a critical component of therapy for children and adults with acute lymphoblastic leukemia (ALL). Allergic reactions, which may occur in up to one third of patients, are the major cause for discontinuation. One study reported lower rates of allergic re...

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Detalles Bibliográficos
Autores principales: Losasso, Michael, Bostrom, Bruce, Messinger, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001754/
https://www.ncbi.nlm.nih.gov/pubmed/32089823
http://dx.doi.org/10.12688/f1000research.19298.2