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Cohesin controls intestinal stem cell identity by maintaining association of Escargot with target promoters

Intestinal stem cells (ISCs) maintain regenerative capacity of the intestinal epithelium. Their function and activity are regulated by transcriptional changes, yet how such changes are coordinated at the genomic level remains unclear. The Cohesin complex regulates transcription globally by generatin...

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Detalles Bibliográficos
Autores principales: Khaminets, Aliaksandr, Ronnen-Oron, Tal, Baldauf, Maik, Meier, Elke, Jasper, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002041/
https://www.ncbi.nlm.nih.gov/pubmed/32022682
http://dx.doi.org/10.7554/eLife.48160