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Single-cell activity tracking reveals that orbitofrontal neurons acquire and maintain a long-term memory to guide behavioral adaptation

Learning to predict rewards based on environmental cues is essential for survival. The orbitofrontal cortex (OFC) contributes to such learning, by conveying reward-related information to brain areas such as the ventral tegmental area (VTA). Despite this, how cue-reward memory representations form in...

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Detalles Bibliográficos
Autores principales: Namboodiri, Vijay Mohan K., Otis, James M., van Heeswijk, Kay, Voets, Elisa S., Alghorazi, Rizk A., Rodriguez-Romaguera, Jose, Mihalas, Stefan, Stuber, Garret D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002110/
https://www.ncbi.nlm.nih.gov/pubmed/31160741
http://dx.doi.org/10.1038/s41593-019-0408-1