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Identification of Clostridioides difficile-Inhibiting Gut Commensals Using Culturomics, Phenotyping, and Combinatorial Community Assembly

A major function of the gut microbiota is to provide colonization resistance, wherein pathogens are inhibited or suppressed below infectious levels. However, the fraction of gut microbiota required for colonization resistance remains unclear. We used culturomics to isolate a gut microbiota culture c...

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Detalles Bibliográficos
Autores principales: Ghimire, Sudeep, Roy, Chayan, Wongkuna, Supapit, Antony, Linto, Maji, Abhijit, Keena, Mitchel Chan, Foley, Andrew, Scaria, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002114/
https://www.ncbi.nlm.nih.gov/pubmed/32019832
http://dx.doi.org/10.1128/mSystems.00620-19