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Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458

During endoderm formation, cell identity and tissue morphogenesis are tightly controlled by cell-intrinsic and cell-extrinsic factors such as biochemical and physical inputs. While the effects of biochemical factors are well studied, the physical cues that regulate cell division and differentiation...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Fan, Li, Yi-Shuan J., Chou, Chih-Hung, Chiew, Men Yee, Huang, Hsien-Da, Ho, Jennifer Hui-Chun, Chien, Shu, Lee, Oscar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002135/
https://www.ncbi.nlm.nih.gov/pubmed/32076643
http://dx.doi.org/10.1126/sciadv.aay0264