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Animal simulations facilitate smart drug design through prediction of nanomaterial transport to individual tissue cells

Smart drug design for antibody and nanomaterial-based therapies allows optimization of drug efficacy and more efficient early-stage preclinical trials. The ideal drug must display maximum efficacy at target tissue sites, with transport from tissue vasculature to the cellular environment being critic...

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Detalles Bibliográficos
Autores principales: Price, Edward, Gesquiere, Andre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002136/
https://www.ncbi.nlm.nih.gov/pubmed/32076633
http://dx.doi.org/10.1126/sciadv.aax2642