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ICAM5 as a Novel Target for Treating Cognitive Impairment in Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability, resulted from the silencing of the Fmr1 gene and the subsequent loss of fragile X mental retardation protein (FMRP). Spine dysgenesis and cognitive impairment have been extensively characterized in FXS; however, t...

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Detalles Bibliográficos
Autores principales: Pei, Ya-ping, Wang, Yue-yi, Liu, Dan, Lei, Hui-yang, Yang, Zhi-hao, Zhang, Zi-wei, Han, Man, Cheng, Ke, Chen, Yu-shan, Li, Jin-quan, Cheng, Gui-rong, Xu, Lang, Wu, Qing-ming, McClintock, Shawn M., Yang, Ying, Zhang, Yong, Zeng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002157/
https://www.ncbi.nlm.nih.gov/pubmed/31882402
http://dx.doi.org/10.1523/JNEUROSCI.2626-18.2019