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Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells

The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by favoring the chemoresistance of AML cells. Intimate interactions between leukemic cells and BM mesenchymal stromal cells (BM-MSCs) play key roles in this process. Direct intercellular communications between hematop...

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Detalles Bibliográficos
Autores principales: Kouzi, Farah, Zibara, Kazem, Bourgeais, Jerome, Picou, Frederic, Gallay, Nathalie, Brossaud, Julie, Dakik, Hassan, Roux, Benjamin, Hamard, Sophie, Le Nail, Louis-Romee, Hleihel, Rita, Foucault, Amelie, Ravalet, Noemie, Rouleux-Bonnin, Florence, Gouilleux, Fabrice, Mazurier, Frederic, Bene, Marie C., Akl, Haidar, Gyan, Emmanuel, Domenech, Jorge, El-Sabban, Marwan, Herault, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002301/
https://www.ncbi.nlm.nih.gov/pubmed/31649334
http://dx.doi.org/10.1038/s41388-019-1069-y