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The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

The filamentous fungus Aspergillus fumigatus can cause a distinct set of clinical disorders in humans. Invasive aspergillosis (IA) is the most common life-threatening fungal disease of immunocompromised humans. The mitogen-activated protein kinase (MAPK) signaling pathways are essential to the adapt...

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Detalles Bibliográficos
Autores principales: Mattos, Eliciane Cevolani, Silva, Lilian Pereira, Valero, Clara, de Castro, Patrícia Alves, dos Reis, Thaila Fernanda, Ribeiro, Liliane F. C., Marten, Mark R., Silva-Rocha, Rafael, Westmann, Cauã, da Silva, Carlos Henrique Tomich de Paula, Taft, Carlton Anthony, Al-Furaiji, Narjes, Bromley, Michael, Mortensen, Uffe H., Benz, J. Philipp, Brown, Neil Andrew, Goldman, Gustavo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002344/
https://www.ncbi.nlm.nih.gov/pubmed/32019798
http://dx.doi.org/10.1128/mBio.02962-19