Reducing Aspergillus fumigatus Virulence through Targeted Dysregulation of the Conidiation Pathway

Inhalation of conidia of the opportunistic mold Aspergillus fumigatus by immunocompromised hosts can lead to invasive pulmonary disease. Inhaled conidia that escape immune defenses germinate to form filamentous hyphae that invade lung tissues. Conidiation rarely occurs during invasive infection of t...

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Detalles Bibliográficos
Autores principales: Stewart, James I. P., Fava, Vinicius M., Kerkaert, Joshua D., Subramanian, Adithya S., Gravelat, Fabrice N., Lehoux, Melanie, Howell, P. Lynne, Cramer, Robert A., Sheppard, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002347/
https://www.ncbi.nlm.nih.gov/pubmed/32019801
http://dx.doi.org/10.1128/mBio.03202-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002347/
https://www.ncbi.nlm.nih.gov/pubmed/32019801
http://dx.doi.org/10.1128/mBio.03202-19

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