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Calreticulin Blockade Attenuates Murine Acute Lung Injury by Inducing Polarization of M2 Subtype Macrophages

Calreticulin (CALR) has anti-tumor effects by increasing dendritic cell maturation and tumor antigen presentation. However, whether CALR affects macrophages and modulates progression of acute respiratory distress syndrome/acute lung injury (ARDS/ALI) remains unknown. In this study, we discovered tha...

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Detalles Bibliográficos
Autores principales: Jiang, Zhilong, Chen, Zhihong, Hu, Lu, Qiu, Lin, Zhu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002388/
https://www.ncbi.nlm.nih.gov/pubmed/32082309
http://dx.doi.org/10.3389/fimmu.2020.00011