Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

The type and genomic context of cancer mutations depend on their causes. These causes have been characterized using signatures that represent mutation types that co-occur in the same tumours. However, it remains unclear how mutation processes change during cancer evolution due to the lack of reliabl...

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Detalles Bibliográficos
Autores principales: Rubanova, Yulia, Shi, Ruian, Harrigan, Caitlin F., Li, Roujia, Wintersinger, Jeff, Sahin, Nil, Deshwar, Amit G., Morris, Quaid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002414/
https://www.ncbi.nlm.nih.gov/pubmed/32024834
http://dx.doi.org/10.1038/s41467-020-14352-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002414/
https://www.ncbi.nlm.nih.gov/pubmed/32024834
http://dx.doi.org/10.1038/s41467-020-14352-7

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