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RefDNN: a reference drug based neural network for more accurate prediction of anticancer drug resistance

Cancer is one of the most difficult diseases to treat owing to the drug resistance of tumour cells. Recent studies have revealed that drug responses are closely associated with genomic alterations in cancer cells. Numerous state-of-the-art machine learning models have been developed for prediction o...

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Detalles Bibliográficos
Autores principales: Choi, Jonghwan, Park, Sanghyun, Ahn, Jaegyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002431/
https://www.ncbi.nlm.nih.gov/pubmed/32024872
http://dx.doi.org/10.1038/s41598-020-58821-x