Glucose‐induced oxidative stress and accelerated aging in endothelial cells are mediated by the depletion of mitochondrial SIRTs

Diabetic complications cause significant morbidity and mortality. Dysfunction of vascular endothelial cells (ECs), caused by oxidative stress, is a main mechanism of cellular damage. Oxidative stress accelerates EC senescence and DNA damage. In this study, we examined the role of mitochondrial sirtu...

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Detalles Bibliográficos
Autores principales: Liu, Jieting, Chen, Shali, Biswas, Saumik, Nagrani, Niharika, Chu, Yanhui, Chakrabarti, Subrata, Feng, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002531/
https://www.ncbi.nlm.nih.gov/pubmed/32026628
http://dx.doi.org/10.14814/phy2.14331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002531/
https://www.ncbi.nlm.nih.gov/pubmed/32026628
http://dx.doi.org/10.14814/phy2.14331

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