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Role of sodium‐dependent Pi transporter/Npt2c on Pi homeostasis in klotho knockout mice different properties between juvenile and adult stages

SLC34A3/NPT2c/NaPi‐2c/Npt2c is a growth‐related NaPi cotransporter that mediates the uptake of renal sodium‐dependent phosphate (Pi). Mutation of human NPT2c causes hereditary hypophosphatemic rickets with hypercalciuria. Mice with Npt2c knockout, however, exhibit normal Pi metabolism. To investigat...

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Detalles Bibliográficos
Autores principales: Hanazaki, Ai, Ikuta, Kayo, Sasaki, Shohei, Sasaki, Sumire, Koike, Megumi, Tanifuji, Kazuya, Arima, Yuki, Kaneko, Ichiro, Shiozaki, Yuji, Tatsumi, Sawako, Hasegawa, Tomoka, Amizuka, Norio, Miyamoto, Ken‐ichi, Segawa, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002534/
https://www.ncbi.nlm.nih.gov/pubmed/32026654
http://dx.doi.org/10.14814/phy2.14324