Cargando…

Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Long-term use of imatinib is effective and well-tolerated in children with chronic myeloid leukaemia (CML) yet defining an optimal dosing regimen for imatinib in younger patients is a challenge. The potential interactions between imatinib and coadministered drugs in this “special” population also re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adiwidjaja, Jeffry, Boddy, Alan V., McLachlan, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002565/ https://www.ncbi.nlm.nih.gov/pubmed/32082165 http://dx.doi.org/10.3389/fphar.2019.01672

Ejemplares similares

Physiologically Based Pharmacokinetic Modeling Approaches for Patients With SARS‐CoV‐2 Infection: A Case Study With Imatinib
por: Adiwidjaja, Jeffry, et al.
Publicado: (2022)

A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study
por: Adiwidjaja, Jeffry, et al.
Publicado: (2018)

Application of physiologically based pharmacokinetic modeling to understand real‐world outcomes in patients receiving imatinib for chronic myeloid leukemia
por: Adattini, Josephine A., et al.
Publicado: (2023)

Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance
por: Chan, Wai-Jo Jocelin, et al.
Publicado: (2023)

Pharmacokinetics of caspofungin acetate to guide optimal dosing in cats
por: Leshinsky, Jana, et al.
Publicado: (2017)

Population pharmacokinetic analysis and dosing regimen optimization of teicoplanin in critically ill patients with sepsis
por: Chen, Chao‐Yang, et al.
Publicado: (2023)

Population Pharmacokinetics and Dosing Regimen Optimization of Meropenem in Cerebrospinal Fluid and Plasma in Patients with Meningitis after Neurosurgery
por: Lu, Cheng, et al.
Publicado: (2016)

Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug‐Drug Interactions and Pediatric Dose Regimens
por: Cohen‐Rabbie, Sarit, et al.
Publicado: (2021)

Physiologically based pharmacokinetic modeling of daptomycin dose optimization in pediatric patients with renal impairment
por: Ye, Lingling, et al.
Publicado: (2022)

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder
por: Jin, Zi-bin, et al.
Publicado: (2022)

Physiologically-based pharmacokinetic modeling for single and multiple dosing regimens of ceftriaxone in healthy and chronic kidney disease populations: a tool for model-informed precision dosing
por: Alasmari, Fawaz, et al.
Publicado: (2023)

Optimization of Initial Dose Regimen for Sirolimus in Pediatric Patients With Lymphangioma
por: Chen, Xiao, et al.
Publicado: (2021)

Development of a Physiologically Based Pharmacokinetic Model for Hydroxychloroquine and Its Application in Dose Optimization in Specific COVID-19 Patients
por: Zhang, Miao, et al.
Publicado: (2021)

Application of a Physiologically Based Pharmacokinetic Model to Characterize Time-dependent Metabolism of Voriconazole in Children and Support Dose Optimization
por: Zhang, Yahui, et al.
Publicado: (2021)

Safety and Pharmacokinetics of the Aminomethylcycline Antibiotic Omadacycline Administered to Healthy Subjects in Oral Multiple-Dose Regimens
por: Bundrant, Lu Ann, et al.
Publicado: (2018)

Pharmacokinetic-Pharmacodynamic Target Attainment Analyses as Support for Meropenem-Vaborbactam Dosing Regimens and Susceptibility Breakpoints
por: Bhavnani, S. M., et al.
Publicado: (2022)

Combination Therapy With Rapamycin and Low Dose Imatinib in Pulmonary Hypertension
por: Shi, Yinan, et al.
Publicado: (2021)

Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects
por: Zhou, Ying, et al.
Publicado: (2018)

Population Pharmacokinetics and Dose Optimization of Ganciclovir in Critically Ill Children
por: Li, SiChan, et al.
Publicado: (2021)

A model-based approach for a practical dosing strategy for the short, intensive treatment regimen for paediatric tuberculous meningitis
por: Wasmann, Roeland E., et al.
Publicado: (2023)

Optimized Dosing Regimens of Meropenem in Septic Children Receiving Extracorporeal Life Support
por: Wang, Yixue, et al.
Publicado: (2021)

Corrigendum: Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects
por: Zhou, Ying, et al.
Publicado: (2019)

Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing
por: Ali, Ali Mohamed, et al.
Publicado: (2018)

Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants
por: Zhao, Yang, et al.
Publicado: (2020)

Population Pharmacokinetics and Model-Based Dosing Optimization of Teicoplanin in Pediatric Patients
por: Zhang, Tao, et al.
Publicado: (2020)

Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients
por: Fu, Wen-Qian, et al.
Publicado: (2022)

Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis
por: Dorajoo, Sreemanee Raaj, et al.
Publicado: (2019)

Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK
por: Zazo, Hinojal, et al.
Publicado: (2022)

Physiologic and pharmacokinetic changes in pregnancy
por: Costantine, Maged M.
Publicado: (2014)

Prediction for Plasma Trough Concentration and Optimal Dosing of Imatinib under Multiple Clinical Situations Using Physiologically Based Pharmacokinetic Modeling
por: Gao, Dongmei, et al.
Publicado: (2023)

Population pharmacokinetic analysis and dosing optimization of polymyxin B in critically ill patients
por: Liang, Danhong, et al.
Publicado: (2023)

Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition
por: Beaudoin, James J., et al.
Publicado: (2023)

Imatinib, sunitinib and pazopanib: From flat‐fixed dosing towards a pharmacokinetically guided personalized dose
por: Westerdijk, Kim, et al.
Publicado: (2020)

Physiologically-Based Pharmacokinetics Modeling for Hydroxychloroquine as a Treatment for Malaria and Optimized Dosing Regimens for Different Populations
por: Zhai, Jingchen, et al.
Publicado: (2022)

Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation
por: Niu, Chang-He, et al.
Publicado: (2020)

Population Pharmacokinetics of Antimalarial Naphthoquine in Combination with Artemisinin in Tanzanian Children and Adults: Dose Optimization
por: Ali, Ali Mohamed, et al.
Publicado: (2022)

Optimizing Antimicrobial Therapy by Integrating Multi-Omics With Pharmacokinetic/Pharmacodynamic Models and Precision Dosing
por: Yow, Hui-Yin, et al.
Publicado: (2022)

ABCG2 Single Nucleotide Polymorphism Affects Imatinib Pharmacokinetics in Lower Alpha-1-Acid Glycoprotein Levels in Humans
por: Park, Jin-Woo, et al.
Publicado: (2021)

Unraveling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling
por: Yang, Xiaoxia, et al.
Publicado: (2015)

Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer
por: Walsh, Christopher, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tqrf31thfoj7vfet0dpt85nf4o