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LncRNA RUNX1-IT1 which is downregulated by hypoxia-driven histone deacetylase 3 represses proliferation and cancer stem-like properties in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is characterised by a hypoxic microenvironment and a high rate of heterogeneity and recurrence, and the presence of cancer stem cells (CSCs) in HCC may well explain both of these pathological properties. There is mounting evidence that long non-coding RNAs (lncRNAs) pa...

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Detalles Bibliográficos
Autores principales: Sun, Liankang, Wang, Liang, Chen, Tianxiang, Shi, Yu, Yao, Bowen, Liu, Zhikui, Wang, Yufeng, Li, Qing, Liu, Runkun, Niu, Yongshen, Tu, Kangsheng, Liu, Qingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002583/
https://www.ncbi.nlm.nih.gov/pubmed/32024815
http://dx.doi.org/10.1038/s41419-020-2274-x