A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

In cancer, the primary tumour’s organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium,...

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Detalles Bibliográficos
Autores principales: Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Getz, Gad, Morris, Quaid D., Stein, Lincoln D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002586/
https://www.ncbi.nlm.nih.gov/pubmed/32024849
http://dx.doi.org/10.1038/s41467-019-13825-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002586/
https://www.ncbi.nlm.nih.gov/pubmed/32024849
http://dx.doi.org/10.1038/s41467-019-13825-8

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