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Pan-cancer analyses of human nuclear receptors reveal transcriptome diversity and prognostic value across cancer types

The human nuclear receptor (NR) superfamily comprises 48 ligand-dependent transcription factors that play regulatory roles in physiology and pathophysiology. In cancer, NRs have long served as predictors of disease stratification, treatment response, and clinical outcome. The Cancer Genome Atlas (TC...

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Detalles Bibliográficos
Autor principal: Parris, Toshima Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002682/
https://www.ncbi.nlm.nih.gov/pubmed/32024906
http://dx.doi.org/10.1038/s41598-020-58842-6