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Pan-cancer analyses of human nuclear receptors reveal transcriptome diversity and prognostic value across cancer types
The human nuclear receptor (NR) superfamily comprises 48 ligand-dependent transcription factors that play regulatory roles in physiology and pathophysiology. In cancer, NRs have long served as predictors of disease stratification, treatment response, and clinical outcome. The Cancer Genome Atlas (TC...
Autor principal: | Parris, Toshima Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002682/ https://www.ncbi.nlm.nih.gov/pubmed/32024906 http://dx.doi.org/10.1038/s41598-020-58842-6 |
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