Transcriptional effects of copy number alterations in a large set of human cancers

Copy number alterations (CNAs) can promote tumor progression by altering gene expression levels. Due to transcriptional adaptive mechanisms, however, CNAs do not always translate proportionally into altered expression levels. By reanalyzing >34,000 gene expression profiles, we reveal the degree o...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002723/
https://www.ncbi.nlm.nih.gov/pubmed/32024838
http://dx.doi.org/10.1038/s41467-020-14605-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002723/
https://www.ncbi.nlm.nih.gov/pubmed/32024838
http://dx.doi.org/10.1038/s41467-020-14605-5

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